Efficacy of Ketamine in the Treatment of Substance Use Disorders: A Systematic Review
Background: Despite advances 644 in behavioral and pharmacotherapy interventions, substance use disorders (SUDs) are frequently refractory to treatment.Glutamatergic dysregulation has received increasing attention as one common neuropathology across multiple substances of abuse.Ketamine is a potent N-methyl-D-aspartate (NMDA) glutamatergic receptor